Effect of sodium fluoride in maternal and offspring rats and its amelioration

Effect of sodium fluoride in maternal and offspring rats and its amelioration

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High fluoride content is known to cause dental and skeletal abnormalities.In addition, present review indicates that sodium fluoride consumption caused increased number of r=esorptions and dead foetuses.Various skeletal anomalies such acupatch as wavy ribs, presence of 14th ribs, lacking 6th sternebrae and incompete ossification of skull occur.All these changes could be due to coq-clear 100 ubiquinol oxidative stress caused by fluoride consumption.

Fluoride-induced changes could be successfully ameliorated by cotreatment with vitamins and calcium.